eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2019-02-16 3 2(a) 33091 article C.B. Nwachukwu 1 C. Azoro 2 A. Idris 1 G.N. Wokem 3 Microbiology/Biochemistry Unit, Department of Science Laboratory Technology, Federal Polytechnic, P.M.B. 0231, Bauchi, Nigeria. Department of General Studies, Federal Polytechnic, P.M.B. 0231 Bauchi, Nigeria. Department of Medical Laboratory Technology, River State University of Science and Technology, Port Harcourt, Nigeria. The antibacterial activities of methanol and aqueous extracts of the leaf of Mitracarpus scaber on Staphylococcus aureus were studied. Phytochemical analysis of the extracts was also done. Results of the antibacterial activity studies showed that both the methanol and aqueous leaf extracts were active against Staphylococcus aureus in vitro. The methanol extract gave a range of 5.0-5.8mm zone of inhibition, while the aqueous extract gave a range of 3.5-5.8 mm on agar plates both in the different dilutions used. The result of the phytochemical analysis revealed that flavonoids tannins, alkaloids, carbohydrates (sugars), glycosides, saponins and resins were present. https://www.biotech-asia.org/vol3no2a/antibacterial-activity-of-methanol-and-aqueous-leaf-extracts-of-mitracarpus-scaber-on-staphylococcus-aureus/ Antibacterial activity; Mitracarpus scaber; Staphylococcus aureus