eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2020-07-31 3 2a 36647 article Neeraj Sharma 1 P.K. Sharma 1 Nisha Mary Joseph 1 Mayank Bansal 1 KIET School of Pharmacy, Gaziabad (India) Inflammatory² bowel diseases including irritable bowl syndrome, ulcerative colitis and crohn’s disease are considered serious colonic disorder. Ulcerative colotis, if not treated, leads to colon cancer. More than 66,000 cases of colon cancer are reported to occur every year in India. Cancer of large intestine accounts for about 15% of cancer death in India. Oral delivery has become a widely accepted route of administration of therapeutic drug, the gastrointestinal³ tract present several formidable barrier to drug delivery. Colonic drug delivery is also found useful for improving systemic absorption of drug like nitrendipine, metoprolol, theophylline, isosorbide Mônonitrate. https://www.biotech-asia.org/vol3no2a/colon-targeted-drug-delivery-system-a-review/ Bowel Diseases Gastrointestinal Tract Isosorbide Mônnitrate Metoprolol   Nitrendipine Theophylline Ulcerative Colitis