eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2020-08-21 3 2a 36842 article Anita Tilwari 1 N.P. Shukla 2 Anita Tilwari¹*, N.P. Shukla² and P. Uma Devi³ 3 School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya and Peoples Group of Medical Sciences and Research Centre, Bhopal - 462 036 India M.P. Council of Science and Technology, Bhopal - 462 023 India Department of Research, Jawaharlal Nehru Cancer Hospital and Research Centre, Bhopal - 462 001 India Tribulus terrestris is highly valued in Indian system of medicine and extensively used for tonic and rejuvenating properties. Therefore, this study was aimed to evaluate the effect of aqueous extract of tribulus terrestris on non specific immunity in rats. Adult healthy Wistar rats weighing 150 g-200 g were injected intraperitoneally with 0.5mg, 1mg or 2mg per kg body weight of the extract daily for 7 days. Parameters of the study included body weight, organ weight, peritoneal exudate cells (PEC) counts and phagocytic activity of PEC. Results indicate that all doses of aqueous extract of Tribulus terrestris significantly (p<0.001) increased counts of peritoneal macrophages and stimulated phagocytic index of macrophages. https://www.biotech-asia.org/vol3no2a/augmentation-of-non-specific-immunity-in-rats-by-aqueous-extract-of-tribulus-terrestris-used-in-traditional-systems-of-medicines/ Macrophages; Non-Specific Immunity; Peritoneal Cavity; Peritoneal Exudate Cells (PEC); Traditional System of Medicine